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Ganoderma lucidum has been widely used in Asian countries for hundreds of years to promote health and longevity. The pharmacological functions of which had been reported, are the activation of innate immune responses, suppression of tumour and modulation of cell proliferations. Effective fractions of Ganoderma lucidum polysaccharides had already been reported to regulate the immune system. In recent years, studies on the neuroprotective effects of G. lucidum have begun to intensify. G. lucidum is believed to have a neuro-protective effect and this notion is supported by work carried out by scientists. Spesifically wherein a mixture of triterpenoid compounds in G. lucidum promoted neuronal survival and reduced fatigue. In addition, the potential use of this fungus for the treatment of neurological diseases has also been examined. It was shown that long-term consumption of G. lucidum can decrease the progression of Alzheimer’s disease. This observed neuroprotective effect is achieved by promotion of neuritogenesis and reduction of senescence of the neurons. To summarize the studies on the neuroprotective effects of the intended G. lucidum, we want to shed some light on those who wish to study in this regard.
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